Health & Genetics

Legge-Calves- Perthes in Manchester Terriers

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In 1989, the University of California (Davis) conducted a test breeding of two Toy Manchesters clinically affected with Legge-Calves-Perthes ("LCP")disease.  The conclusion was that LCP is an inherited disorder in Manchester Terriers with a high heritability (i.e., the influence of breeding is very strong on the dog's potential for developing the disorder), and the study has long been considered the 'seminal' study on the disease.  An abstract, "Mode of Inheritance of Perthes' Disease in Manchester Terriers" can be found on PubMed.